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Gluten sensitive | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex

Could You Be Gluten Sensitive Without Celiac Disease?

By:
Marnie Luck, ND
Last Updated: March 27, 2025
Article contents

To eat, or not to eat wheat? That is the question.

The avoidance of gluten continues to be a hot topic in the media.

More and more people are opting for a gluten-free diet. For some people, eliminating gluten from their diet may be essential to not only maintaining the integrity of their gastrointestinal tract, but optimizing their overall health.

Digestion is the cornerstone of good health. If a person’s digestive capacity is impaired, many other areas of a person’s health can be adversely affected.

Not everyone who has a bad reaction to gluten has celiac disease. Non-celiac gluten sensitivity (NCGS) also negatively affects on the body, but does not produce the same disease process or complications that celiac disease does.

The naturopathic doctors at Annex Naturopathic Clinic are able to assess, diagnose and treat celiac disease and NCGS.

Dr. Luck and Dr. Lee can help determine whether or not you can include gluten in your diet and what treatment needs to be in place to heal the gut.

What is gluten?

Gluten is a protein found in wheat and some other grains including rye and barley.

What is celiac disease?

Celiac disease is an autoimmune condition.

Gluten causes the immune system to destroy intestinal cells. When intestinal cells are destroyed they lose their capacity to absorb nutrients causing chronic diarrhea, nutrient deficiencies and weight loss.

Celiac disease is associated with a much more serious risk profile than NCGS including neurologic dysfunction, osteoporosis, infertility, and other autoimmune diseases such as rheumatoid arthritis and Hashimoto’s thyroiditis.

Why does celiac disease happen?

Genetics plays a strong role in whether or not someone will have celiac disease.

How is celiac disease diagnosed?

Serology (blood) testing for the antibodies against the intestinal tissues (endomysial antibodies (IgA EMA) and tissue transglutaminase antibodies (IgA tTG)).

If the antibodies are more than twice the normal limit, the patient likely has celiac disease.

Duodenal biopsy, tissue samples taken from the small intestine (which can only be ordered by a gastroenterologist), can confirm the serology testing.

These tests will only be accurate if the patient has ingested gluten consistently over the past 6 weeks.

What is non-celiac gluten sensitivity (NCGS)?

NCGS is a reaction to gluten that does not involve the immune system and does not cause intestinal cell destruction. Gastrointestinal symptoms include abdominal pain, bloating, constipation and diarrhea. NCGS can also contribute to joint and muscle pain, skin rash, anemia and depression.

Why does NCGS happen?

The working theory as to the increased prevalence of NCGS is a combination of increased wheat consumption and the hybridized gluten content of wheat- today’s wheat contains far more gluten than it’s ancient ancestor.

How is NCGS diagnosed?

NCGS is a diagnosis of exclusion.

When celiac disease has been ruled out, there are no signs of malabsorption and the individual has improves on a gluten-free diet, a diagnosis of NCGS can be assumed.

If you are experiencing adverse reactions to gluten it is important to have a thorough work-up.

Marnie Luck
Written By:
Marnie Luck

Dr. Marnie Luck, ND, possesses an academic background from McGill University and the Canadian College of Naturopathic Medicine. With distinctive certifications in pelvic floor therapy and menopause management, she combines her expertise to provide comprehensive naturopathic care.

Our Editorial Process

Annex Naturopathic Clinic is committed to creating high quality and medically reviewed content to help educate readers on subjects related to their health and wellness. Here is how we achieve this goal:

Writing: Our content is meticulously researched and written by our practitioners who source details from highly-respected databases, academic journals, and scientific articles in the field of medicine and healthcare. Our practitioners also include insights from their robust clinical practices.

Editing: Each article is carefully edited by a peer reviewer (a senior practitioner) to ensure accuracy, clarity, and relevance.

Medically Verified: The article is thoroughly reviewed and verified by a registered naturopathic doctor from Annex Naturopathic Clinic to ensure the factual accuracy of medical facts, assumptions, and interpretations within the content.

If you’re curious to learn more about this subject or would like to consult with one of our practitioners feel free to book a visit or contact us.

Yours in Health,

Annex Naturopathic Clinic
800 Bathurst St Suite 301,
Toronto, ON M5R 3M8

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Annex Naturopathic Clinic is a clinic in Toronto that offers integrative healthcare solutions from experienced practitioners.

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